Myricetin

Name: Myricetin
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP0970

CAS NO.: 529-44-2

Purity: 98%

Brand: Biopurify

Botanical Source: Curculigo orchioides Gaertn.

Myricetin, a natural flavonoid with anti-amyloidogenic, anti-oxidant, anticancer, antidiabetic and anti-inflammatory properties, is a novel inhibitor of MEK1 activity and inhibits glucose uptake in isolated rat adipocytes . It also inhibits PI3Kγ with Kd of 0.17 μM. Myricetin exerts potent anti-photoaging activity by regulating MMP-9 expression through the suppression of Raf kinase activity. Myricetin can enhance osteogenic differentiation of hBMSCs by activating the Wnt/β-catenin signaling. Myricetin is a hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants. It has a role as a geroprotector, an antioxidant, a hypoglycemic agent, an antineoplastic agent, a cyclooxygenase 1 inhibitor, a plant metabolite and a food component. It is a hexahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a myricetin(1-).

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Related diseases

Alzheimer's Disease Type 2 Diabetes Mellitus Non-alcoholic Steatohepatitis Antioxidant damage Colorectal Cancer

Related targets

Alzheimer's Disease PTPN1 APP BACE1 BCL2 AMPK MAPT AKR1B1 NFE2L2 GAA TNF MAOB GSK3B ACHE PPARG PIK3CA MMP9 PTGS2 NFKB1 AKT1 CASP3 NRF2 SOD1 CAT GPX1 HMOX1 CTNNB1 BDNF GRIN1

Type 2 Diabetes Mellitus PTPN1 APP AMPK AKR1B1 NFE2L2 GAA TNF GSK3B PPARG PIK3CA SREBF1 PTGS2 NFKB1 AKT1 DPP4 SOD1 CAT GPX1 HMOX1 TGFB1 IRS1 SLC2A4 FASN PPARA

Non-alcoholic Steatohepatitis PTPN1 BCL2 AMPK NFE2L2 TNF PPARG SREBF1 PTGS2 NFKB1 CASP3 SOD1 GPX1 HMOX1 TGFB1 FASN CYP2E1 PPARA

Antioxidant damage NFE2L2 NRF2 SOD1 CAT GPX1 HMOX1

Colorectal Cancer BCL2 AMPK NFE2L2 TNF GSK3B PPARG PIK3CA MMP9 PTGS2 TP53 NFKB1 AKT1 CDK2 CASP3 SOD1 TGFB1 FASN CTNNB1 VEGFA PPARA

Product description Related Products Prediction Parameters Reference Literature

Product name: Myricetin
Synonym name: Cannabiscetin; Myricetol
Catalogue No.: BP0970
Cas No.: 529-44-2
Formula: C₁₅H₁₀O₈
Mol Weight: 318.237
Botanical Source: Myrica rubra (Lour.) S. et Zucc.
Physical Description:
Type of Compound: Flavonoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams
Inquire for bulk scale.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，TCM), Natural Active Pharmaceutical Ingredients worldwide.
The main services:
A. Supply active ingredients and reference standards of TCM, from mgs to kgs scale
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR(contract research), CM(contract manufacture) and PD(process development) services from lab scale, pilot scale to commercial scale(GMP is also available)
E. TCM compounds library for drug screen,more than 3000 compounds available, many of them are rare and unique.