Ginsenoside F1

Name: Ginsenoside F1
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP0652

CAS NO.: 53963-43-2

Purity: 98%

Brand: Biopurify

Botanical Source:

Ginsenoside has been reported to suppress platelet aggregation and to reduce gap junction-mediated intercellular communication, also as a novel anti-skin cancer drug with anti-proliferative and anti-migration features. Ginsenoside F1 has a potential for industrial cosmetic materials, it also has inhibitory effect of elastase and tyrosinase, it significantly reduces ultraviolet-B-induced cell death by maintaining constant levels of Bcl-2 and protects HaCaT cells from apoptosis caused by ultraviolet B irradiation. Ginsenoside F1 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as an apoptosis inhibitor and a plant metabolite.

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BP0652-100mg	100mg	Sign in	Sign in
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Related diseases

Alzheimer's Disease Non-alcoholic fatty liver disease Osteoporosis Melanoma Immunomodulation

Related targets

Alzheimer's Disease BACE1 STAT3 AMPK CASP1 RELA ESR1 TNF GSK3B ACHE PPARG AKT1 CTNNB1 IL10 GRIN1

Non-alcoholic fatty liver disease STAT3 AMPK CASP1 RELA ESR1 TNF ACHE PPARG SREBF1 AKT1 TGFB1 IL10

Osteoporosis STAT3 AMPK RELA ESR1 TNF GSK3B PPARG AKT1 TGFB1 CTNNB1 CTSK TNFRSF11B

Melanoma STAT3 AMPK RELA TNF AKT1 MAP2K1 CTNNB1 CDK4

Immunomodulation STAT3 IL2 TGFB1 IL10 FOXP3

Product description Related Products Prediction Parameters Reference Literature

Product name: Ginsenoside F1
Synonym name:
Catalogue No.: BP0652
Cas No.: 53963-43-2
Formula: C₃₆H₆₂O₉
Mol Weight: 638.883
Botanical Source: Panax spp.
Physical Description: White powder
Type of Compound: Triterpenoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.

Descriptions:
Ginsenoside (G)-F1 is an enzymatic metabolite generated from G-Rg1, it has been reported to suppress platelet aggregation and to reduce gap junction-mediated intercellular communication, also as a novel anti-skin cancer drug with anti-proliferative and anti-migration features.[1]
Ginsenoside F1 significantly reduces ultraviolet-B-induced cell death by maintaining constant levels of Bcl-2 and protects HaCaT cells from apoptosis caused by ultraviolet B irradiation. [2]
Ginsenoside F1(GF1) has beneficial effects on skin, it reduces α-melanocyte-stimulating hormone-induced melanin secretion in B16F10 cell culture media by 60%, but does not suppress intracellular melanin levels, tyrosinase activity and expression; it primarily modulates the Rho family GTPases resulting in dendrite retraction, suggests that GF1 could act as a potent skin-whitening agent.[3]
Ginsenoside F1 has inhibitory effect of elastase and tyrosinase, indicates that ginsenoside F1 have a potential for industrial cosmetic materials.[4]

References:
[1] Yoo D S, Rho H S, Yong G L, et al. J Ginseng Res, 2011, 35(1):86-91.
[2] Lee E H, Cho S Y, Kim SJShin E S, et al.J Invest Dermatol, 2003, 121(3):607-13.
[3] Ji H K, Baek E J, Lee E J, et al. Exp Dermatol, 2014, 24(2):150-2.
[4] Hong, S.C., Korean J Pharm, 2013, 44(1):10-5.
[5] Chong G, Gao Y G, Pu Z, et al. Chinese Trad Herbal Drugs, 2014, 45(14):2009-13.