Coptisine

Catalogue No.： BP0390

CAS NO.: 3486-66-6

Purity: 98%

Brand: 普瑞法

Botanical Source:

Coptisine is an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM, it can consequently prevent neuron loss, reduce amyloid plaque formation, and ameliorate impaired cognition, it could as a potential new class of drugs for AD treatment. Coptisine has cardioprotection, anti- hypercholesterolemia, anti-fungal, anti-osteosarcoma, anti-hepatoma and anti-leukaemia activities, it also has antispasmodic and relaxant activity on a guinea-pig ileum. Coptisine is a natural product found in Coptis japonica. It has a role as a metabolite.

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Catalog No	Package	Original Price	Price	Inventory	Quantity	Operating
BP0390-20mg	20mg	Sign in	Sign in
BP0390-100mg	100mg	Sign in	Sign in

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Related diseases

Inflammatory Bowel Disease Rheumatoid arthritis Drug-resistant bacterial infection Depression Tumor Immune Escape

Related targets

Inflammatory Bowel Disease IDO1 STAT3 TNF NFKB1 IL6 TGFB1

Rheumatoid arthritis IDO1 STAT3 TNF NFKB1 IL6 TGFB1

Drug-resistant bacterial infection GYRA GYPB DHFR MECA PENA

Depression IDO1 TNF NFKB1 HTR1A IL6 BDNF CRHR1

Tumor Immune Escape IDO1 STAT3 TGFB1

Product description Related Products Prediction Parameters Reference Literature

Synonym name: 2,3:9,10-Bismethylenedioxyprotoberberine
Catalogue No.: BP0390
Cas No.: 3486-66-6
Formula: C₁₉H₁₄NO₄
Mol Weight: 320.324
Botanical Source: Quaternary alkaloid from Coptis japonica (Ranunculaceae) and many other spp., mostly in the Papaveraceae and Fumariaceae

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.