Chlorogenic acid

Name: Chlorogenic acid
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP0345

CAS NO.: 327-97-9

Purity: 98%

Brand: Biopurify

Botanical Source: Lonicera japonica Thunb.

Chlorogenic acid, a phenolic compound found ubiquitously in plants, is an antioxidant and metal chelator, it has antiviral activity by inhibiting HBV replication, it inhibits the inflammatory reaction in HSE via the suppression of TLR2/TLR9-Myd88 signaling pathways. Some derivatives of chlorogenic acid are hypoglycemic agents and may affect lipid metabolism, chlorogenic acid can improve glucose tolerance, decrease some plasma and liver lipids, and improve mineral pool distribution in vivo. Chlorogenic acid is a cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 3-hydroxy group of quinic acid. It is an intermediate metabolite in the biosynthesis of lignin. It has a role as a plant metabolite and a food component. It is a tannin and a cinnamate ester. It is functionally related to a trans-caffeic acid and a (-)-quinic acid. It is a conjugate acid of a chlorogenate.

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BP0345-20mg	20mg	Sign in	Sign in
BP0345-1000mg	1000mg	Sign in	Sign in

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Related diseases

Type 2 Diabetes Mellitus Non-alcoholic fatty liver disease Hypertension Antioxidant damage Neurodegenerative Diseases (e.g., Alzheimer's Disease)

Related targets

Type 2 Diabetes Mellitus PTPN1 NOS3 NFE2L2 TNF GSK3B PPARG SREBF1 SOD1 CAT GPX1 HMOX1 SLC2A4 PPARA

Non-alcoholic fatty liver disease PTPN1 NFE2L2 TNF ACHE PPARG SREBF1 CASP3 SOD1 GPX1 HMOX1 SLC2A4 PPARA

Hypertension NOS3 TNF ACHE PPARG ACE EDN1

Antioxidant damage NFE2L2 NRF2 SOD1 CAT GPX1 HMOX1

Neurodegenerative Diseases (e.g., Alzheimer's Disease) BACE1 NFE2L2 TNF GSK3B ACHE CASP3 NRF2 HMOX1

Product description Related Products Prediction Parameters Reference Literature

Product name: Chlorogenic acid
Synonym name: Caffeylquinic acid; Caffetannic acid; Helianthic acid; Igasuric acid;
Catalogue No.: BP0345
Cas No.: 327-97-9
Formula: C₁₆H₁₈O₉
Mol Weight: 354.311
Botanical Source:
Physical Description: Powder
Type of Compound: Phenylpropanoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.

Descriptions:
Chlorogenic acid, a phenolic compound found ubiquitously in plants, is an in vitro antioxidant and metal chelator, some derivatives of chlorogenic acid are hypoglycemic agents and may affect lipid metabolism;in vivo, chlorogenic acid can improve glucose tolerance, decrease some plasma and liver lipids, and improve mineral pool distribution.[1]
Chlorogenic acid and caffeic acid have antioxidant property, have effects on intestinal ischemia–reperfusion injury.[2]
Chlorogenic acid has antiviral activity, reduces serum DHBV level in DHBV-infected duckling model, shows inhibitory effect on HBV replication.[3]

References:
[1] Sotillo D V R D, Hadley M. J Nutr Biochem, 2002, 13(12):717-726.
[2] Sato Y, Itagaki S, Kurokawa T, et al.Int J Pharm, 2011, 403(1-2):136-138.
[3] Wang G F, Shi L P, Ren Y D, et al. Antivir Res, 2009, 83(2):186-90.
[4] Li X P, Yu J, Luo J Y, et al.Biomed Chromatogr, 2006, 20(2):206-10.