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Product name: Daidzin
Synonym name: Daidzein 7-O-β-D-glucopyranoside; Daidzoside
Catalogue No.: BP0446
Cas No.: 552-66-9
Formula: C21H20O9
Mol Weight: 416.382
Botanical Source: soya bean meal, roots of Pueraria lobata and shoots of Piptanthus nepalensis. Also from Baptisia spp., Glycine max, Medicago sativa, Thermopsis spp. and others in Leguminosae
Physical Description: Powder
Type of Compound: Flavonoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Daidzin is a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase with a Ki of 40 nM, and uncompetitively with respect to the coenzyme NAD+. [1]
Daidzin has preventive effect on bone loss in ovariectomized rats appears to be due to suppression of bone turnover. [2]
Daidzin in the rhizome of Pueraria lobata are prodrugs, which has antiallergic and antithrombotic activities, can inhibit ADP- and collagen-induced platelet aggregation, produced by intestinal microflora.[3]
Daidzin and puerarin can induce a conformational change of beta-CD, which is compressed in one direction and stretched in the other. [4]
References:
[1] Keung W M, Vallee B L. P Nat Acad Sci USA, 1993, 90(4):1247-51.
[2] Ishida H, Uesugi T, Hirai K, et al. Biol Pharm Bull, 1998, 21(1):62-6.
[3] Choo M K, Park E K, Yoon H K, et al. Biol Pharm Bull, 2002, 25(10):1328-32.
[4] Zhang H, Feng W, Li C, et al. J Phys Chem B, 2010, 114(14):4876-83.
[5] Dong H W, Liu W H, Pharmacy S O, et al. J Pharm Res, 2014, 33(2):73-75.
HPLC of Daidzin
HNMR of Daidzin
Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃
149.8200
.2446
.2431
.9952
.5324
.2753
Low
80.5346
3.6596
Yes
No
Yes
No
Yes
No
1.5
Yes
Yes
Yes
Yes
Shenshuai
Wenjing
Hedandan
