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Vincristine

BP1439
57-22-7
98%
Biopurify
Catharanthus roseus （L.）G. Don
Vincristine-induced nociceptive painful sensation, may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action.Vincristine can treat MM, ERK1/2, Akt, and NF-κB inhibitors are potentially useful as anti-MDR agents for the treatment of Vincristine-resistant MM. An inherited polymorphism in the promoter region of CEP72 was associated with increased risk and severity of Vincristine-related peripheral neuropathy. Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a drug, an antineoplastic agent, a tubulin modulator, a microtubule-destabilising agent and a plant metabolite.
Vincristine View larger image
Catalog No Package Original Price Price Inventory Quantity Operating
BP1439-20mg 20mg

Contacts：400-829-7929，028-82633860，82633397，82633165

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Chengdu Biopurify Phytochemicals Ltd.
Chengdu Biopurify Phytochemicals Ltd.

Related diseases

Acute Lymphoblastic Leukemia Lymphoma Neuroblastoma Gastric cancer Rhabdomyosarcoma

Related targets

BCL2 ABCB1 RELA AKR1C3 CASP3 BAX TUBA1B TUBB CDK1
BCL2 MAPT BAX TUBA1B TUBB KIF11 KIF5B CDK1
BCL2 MAPT ABCC1 AKR1C3 CASP3 MYCN BAX TUBB
BCL2 ABCB1 RELA ABCC1 CASP3 BAX TUBB CDK1
IGF1R BAX TUBB
Product description Related Products Prediction Parameters Reference Literature

Synonym name: Leurocristine; Cristovin; Kyocristine; Leucid; Oncovin; Pericristine; Vincosid; Vincrisul
Catalogue No.: BP1439
Cas No.: 57-22-7
Formula: C46H56N4O10
Mol Weight: 824.972
Botanical Source: Alkaloid from Vinca rosea (Catharanthus roseus) (Apocynaceae)

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.

Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃

Product drug property prediction parameters

  • 171.1700

  • 3.6218

  • 3.3459

  • .0309

  • 1.0295

  • 1.6062

  • Low

  • 85.0798

  • 7.2614

  • No

  • No

  • No

  • No

  • Yes

  • No

  • 0.0

  • Yes

  • No

  • Yes

  • Yes

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