Velutin

Name: Velutin
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP3395

CAS NO.: 25739-41-7

Purity: 98%

Brand: Biopurify

Botanical Source: Curcumae radix

Velutin has strong anti-inflammatory activity, it can effectively inhibit the expression of proinflammatory cytokines TNF-α and IL-6 in low micromole levels by inhibiting NF-κB activation and p38 and JNK phosphorylation. Velutin controls HIF-1α activity during PgLPS-activated osteoclastogenesis probably through modulation of the NF-κB pathway, perhaps it could be used therapeutically to prevent bone loss seen in periodontitis.Velutin can induce apoptosis in tumor cells. Velutin is a dimethoxyflavone that is luteolin in which the hydroxy groups at positions 7 and 3' are replaced by methoxy groups. It has a role as an antioxidant, an antibacterial agent, an anti-allergic agent, a melanin synthesis inhibitor, an anti-inflammatory agent and a plant metabolite. It is a dimethoxyflavone and a dihydroxyflavone. It is functionally related to a 4',5,7-trihydroxy-3'-methoxyflavone.

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Contacts：400-829-7929，028-82633860，82633397，82633165

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Related diseases

Atherosclerosis Osteoporosis Melanoma Anti-inflammatory Allergic Asthma

Related targets

Atherosclerosis BCL2 TYR TNF NOS2 PTGS2 NFKB1 IL6 IL1B LDLR VCAM1 CTSK

Osteoporosis BCL2 TNF NOS2 PTGS2 NFKB1 IL6 IL1B NFATC1 CTSK

Melanoma BCL2 TYR HIF1A TNF NOS2 PTGS2 NFKB1 IL6 MITF NFATC1

Anti-inflammatory TNF NOS2 PTGS2 NFKB1 IL6 IL1B

Allergic Asthma TNF NOS2 PTGS2 NFKB1 HRH1 IL4

Product description Related Products Prediction Parameters Reference Literature

Product name: Velutin
Synonym name:
Catalogue No.: BP3395
Cas No.: 25739-41-7
Formula: C₁₇H₁₄O₆
Mol Weight: 314.293
Botanical Source:
Physical Description: Yellow powder
Type of Compound: Flavonoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.

NMR of Velutin