+86-28-82633987
Product name: Scabertopin
Synonym name:
Catalogue No.: SBP02298
Cas No.: 185213-52-9
Formula: C20H22O6
Mol Weight: 358.39
Botanical Source:
Physical Description:
Type of Compound: Sesquiterpenoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams
Inquire for bulk scale.
The structural types of sesquiterpenes in Elephantopus scaber Linn. mainly involve gimarane-type, guaiacum-type and elemene-type, etc. Ten sesquiterpene compounds were isolated and identified from Elephantopus scaber Linn. Among them, gimarane-type lactones are the main skeleton types of the sesquiterpene lactones of Elephantopus scaber Linn. At present, we isolated and obtained scabertopin，isoxyelephantopin, isoscabertopin with anti-hepatocellular carcinoma cell (SMMC-7721) activity, and deoxyelephantopin, elephantopin, 11,13-dihydrodeoxyelephantopin, and scabertopinol.
Scabertopin have antitumor effects: Gentiana has inhibitory effects on the proliferation of many tumor cells. Local application of the active part of G. licheniformis (100 mg/kg) was able to delay the formation of papillomas, reduce the average number of papillomas and the average body weight of papillomatous rats; soft tissue tumors induced by subcutaneous injection of 20-methylcholanthrene (20-MCA) were significantly affected by intraperitoneal injection of G. licheniformis active part; soft tissue tumors induced by subcutaneous injection of 20-MCA were significantly affected by intraperitoneal injection of 20-MCA (20-MCA) Chemicalbook. significant effect; compared with 20-MCA-induced control group, the extracts of Dictyostelium inhibited the incidence of sarcoma and reduced the diameter of tumors; after intraperitoneal injection of the active parts of Dictyostelium, it significantly inhibited the growth of solid tumors of subcutaneously transplanted Dauer's lymphatic ascites carcinoma cells (DLA) and Euclid's ascites carcinoma cells (EAC) and increased the survival time of the tumor-bearing rats.
HPLC of Scabertopin
Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃
78.9000
2.2338
2.2338
.2398
4.0475
4.9630
High
71.4864
5.8688
No
Yes
No
No
Yes
No
0.0
No
Yes
Yes
Yes
Shenshuai
Wenjing
Hedandan
