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Rubitecan

BP1229
91421-42-0
98%
Biopurify
Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, a prodrug and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It is a delta-lactone, a tertiary alcohol, a C-nitro compound, a pyranoindolizinoquinoline and a semisynthetic derivative. Rubitecan is a novel oral inhibitor of topoisomerase I in the camptothecin class. It shows antitumour activity in patients with refractory pancreatic cancer who have failed prior treatments.
Rubitecan View larger image
Catalog No Package Original Price Price Inventory Quantity Operating
BP1229-20mg 20mg

Contacts：400-829-7929，028-82633860，82633397，82633165

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Chengdu Biopurify Phytochemicals Ltd.
Chengdu Biopurify Phytochemicals Ltd.

Related diseases

Antitumor Ovarian cancer Colorectal Cancer Pancreatic cancer Small Cell Lung Cancer

Related targets

BCL2 TOP1 TOP2A ESR1 EGFR TP53 CDK4 MTOR BRCA2
BCL2 ABCB1 TOP1 TDP1 RELA TOP2A ESR1 EGFR TP53 CDK4 MTOR ATM
CES2 BCL2 ABCB1 TOP1 RELA TOP2A EGFR TP53 CDK4 MTOR UGT1A1 ABCC2 ATM
BCL2 ABCB1 TOP1 TOP2A EGFR TP53 MTOR BRCA2 ATM
BCL2 TOP1 RELA TOP2A EGFR TP53 UGT1A1 ABCC2 ATM
Product description Related Products Prediction Parameters Reference Literature
Synonym name: 9-Nitrocamptothecin
Catalogue No.: BP1229
Cas No.: 91421-42-0
Formula: C20H15N3O6
Mol Weight: 393.355
Botanical Source:

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.

Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃

Product drug property prediction parameters

  • 124.5600

  • 1.7321

  • 1.7321

  • .0084

  • 2.4372

  • 13.0994

  • High

  • 86.7326

  • 3.3692

  • Yes

  • No

  • No

  • No

  • Yes

  • Yes

  • 1.8

  • Yes

  • No

  • No

  • Yes

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