Prunetin

Name: Prunetin
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP1163

CAS NO.: 552-59-0

Purity: 98%

Brand: Biopurify

Botanical Source: Trifolium pratense L.

Prunetin is a hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group. It has a role as a metabolite, an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor, an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor and an anti-inflammatory agent. It is a member of 7-methoxyisoflavones and a hydroxyisoflavone. It is functionally related to a genistein. It is a conjugate acid of a prunetin-5-olate. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones.

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BP1163-20mg	20mg	Sign in	Sign in
BP1163-100mg	100mg	Sign in	Sign in
BP1163-1000mg	1000mg	Sign in	Sign in

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Related diseases

Metabolic disease Osteoporosis Inflammatory disease Antitumor Neurodegenerative disease

Related targets

Metabolic disease AMPK NFE2L2 TNF NOS2 GSK3B PPARG SREBF1 PTGS2 ALDH1A1 IL6 MTOR

Osteoporosis BCL2 AMPK NFE2L2 ESR1 TNF NOS2 GSK3B PPARG PTGS2 IL6 RUNX2 TNFRSF11B MTOR

Inflammatory disease NFE2L2 TNF IKBKB NOS2 PPARG PTGS2 IL6 MTOR

Antitumor BCL2 ESR1 EGFR PTGS2 CDK4 MTOR

Neurodegenerative disease BACE1 BCL2 AMPK NFE2L2 TNF IKBKB NOS2 GSK3B ACHE PPARG EGFR PTGS2 IL6 MTOR

Product description Related Products Prediction Parameters Reference Literature

Synonym name: Padmakastein; Prunusetin
Catalogue No.: BP1163
Cas No.: 552-59-0
Formula: C₁₆H₁₂O₅
Mol Weight: 284.267
Botanical Source: Trifolium pratense L.

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.