Prim-O-glucosylcimifugin

Name: Prim-O-glucosylcimifugin
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP1139

CAS NO.: 80681-45-4

Purity: 98%

Brand: Biopurify

Botanical Source:

Prim-O-glucosylcimifugin is main medicinal component of the traditional Chinese drug Saposhnikovia divaricata, has inhibition on NO production and DPPH free radical, it can inhibit the proliferation of smooth muscle cell stimulated by TNF-α and increase the proportion of G0/G1 phase. PRIM-O-GLUCOSYLCIMIFUGIN is an organic heterotricyclic compound and an oxacycle.

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BP1139-20mg	20mg	Sign in	Sign in
BP1139-100mg	100mg	Sign in	Sign in
BP1139-1000mg	1000mg	Sign in	Sign in

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Related diseases

Inflammatory Bowel Disease Rheumatoid arthritis Neuroprotection Osteoarthritis Acute Lung Injury/Acute Respiratory Distress Syndrome

Related targets

Inflammatory Bowel Disease STAT3 MAPK1 TNF NOS2 ACHE PTGS2 NFKB1 IL6 IL1B JAK2 MMP13 HMGB1

Rheumatoid arthritis STAT3 MAPK1 TNF NOS2 ACHE PTGS2 NFKB1 IL6 IL1B JAK2 CREB1 MMP13 HMGB1

Neuroprotection MAPK1 ACHE CREB1 BDNF NGF

Osteoarthritis STAT3 MAPK1 TNF NOS2 PTGS2 NFKB1 IL6 IL1B CREB1 MMP13

Acute Lung Injury/Acute Respiratory Distress Syndrome TNF NOS2 PTGS2 NFKB1 IL6 IL1B HMGB1

Product description Related Products Prediction Parameters Reference Literature

Product name: Prim-O-glucosylcimifugin
Synonym name: Cimifugin 7-glucoside
Catalogue No.: BP1139
Cas No.: 80681-45-4
Formula: C₂₂H₂₈O₁₁
Mol Weight: 468.455
Botanical Source: Angelica, Diplolophium, Eranthis, Ledebouriella and Saposhnikovia spp
Physical Description: Powder
Type of Compound: Flavonoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.

Descriptions:
Prim-O-glucosylcimifugin is main medicinal component of the traditional Chinese drug Saposhnikovia divaricata, can increase concentrations of astragaloside IV and atractylenolide I in the serum, when they were given together.[1]
Prim-O-glucosylcimifugin has inhibition on NO production and DPPH free radical.[2]
Prim-O-glucosylcimifugin and 4′-O-β-D-glucosyl-5-O-methylvisammin-ol con can inhibit the proliferation of smooth muscle cell stimulated by TNF-α and increase the proportion of G0/G1 phase.[3]

References:
[1] Song J, Zheng S R, Jin Y, et al. Planta Med, 2014, 80(3):187-92.
[2] Bo Z, Xin B Y, Xiu W Y, et al. J Asian Nat Prod Res, 2012, 14(9):886-96.
[3] Wang L, Liang R X, et al. China J Chinese Materia Medica, 2008, 33(17):2157-60.
[4] Pin R, Fang B, Li P, et al. Guiding J Trad Chinese Med Pharm, 2010, 16(11):84-6.