Nortrachelogenin

Catalogue No.： SBP01337

CAS NO.: 34444-37-6

Purity: 98%

Brand: 普瑞法

Botanical Source:

Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors, thereby efficiently synergizing with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), exposure.Nortrachelogenin has anti-inflammatory properties,it shows moderate inhibiting activities on NF- κB signaling pathway induced by TNF-α , with the IC50 value of 49.4 uM. Nortrachelogenin also shows anti-plasmodium activity of 14.50 dg/ml. (+ )-Nortrachelogenin shows effects on the central nervous system producing depression in rabbits, it is moderately active against HIV-1 in vitro. (-)-Nortrachelogenin exerts its antibacterial effect by disorganizing and perturbing the cytoplasmic membrane, it also can induce membrane disruption and caspase-dependent apoptosis.

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Catalog No	Package	Original Price	Price
SBP01337-5mg	5mg	Sign in	Sign in
SBP01337-10mg	10mg	Sign in	Sign in
SBP01337-20mg	20mg	Sign in	Sign in
SBP01337-100mg	100mg	Sign in	Sign in

Contacts：400-829-7929，028-82633860，82633397，82633165

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Related diseases

Alzheimer's Disease Diabetes Mellitus Anti-inflammatory Cancer Fungal infection

Related targets

Alzheimer's Disease APP BCL2 AMPK MAPT AKR1B1 NFE2L2 GAA TNF MAOB ACHE PPARG MMP9 PTGS2 NFKB1 AKT1 CASP3 IL6 IL1B BDNF BAX

Diabetes Mellitus APP AMPK AKR1B1 NFE2L2 GAA TNF MAOB PPARG PTGS2 NFKB1 AKT1 CASP3 IL6 IL1B IRS1 SLC2A4

Anti-inflammatory TNF PTGS2 NFKB1 IL6 IL1B

Cancer BCL2 AMPK NFE2L2 TNF PPARG MMP9 PTGS2 NFKB1 AKT1 CASP3 CCND1 BAX

Fungal infection NFKB1

Product description Related Products Prediction Parameters Reference Literature

Product name: Nortrachelogenin
Synonym name:
Catalogue No.: SBP01337
Cas No.: 34444-37-6
Formula: C₂₀H₂₂O₇
Mol Weight: 374.389
Botanical Source:
Physical Description: Powder
Type of Compound: Lignans

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.