Naringin

Name: Naringin
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP0983

CAS NO.: 10236-47-2

Purity: 98%

Brand: Biopurify

Botanical Source: Aurantii fructus immaturus

Naringin exhibits antioxidant, anti-atherogenic, antiulcer, anti-hypocholesterolemic, anti-lipoperoxidative, and anti-hyperglycemia effects. Naringin reduces Ara-C-induced oxidative stress through both an inhibition of the generation of ROS production and an increase in antioxidant enzyme activities, it blocks apoptosis caused by Ara-C-induced oxidative stress, resulting in the inhibition of the cytotoxicity of Ara-C. Naringin attenuates epidermal growth factor (EGF)-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways. Naringin is a disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent. It is a member of 4'-hydroxyflavanones, a (2S)-flavan-4-one, a neohesperidoside, a dihydroxyflavanone and a disaccharide derivative. It is functionally related to a (S)-naringenin.

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Related diseases

Diabetes Mellitus Hyperlipidemia Liver cancer Osteosarcoma Oxidative Stress-Related Diseases

Related targets

Diabetes Mellitus GCK NFE2L2 PPARG CASP3 DPP4 SOD1 GPX1 SLC2A4 INSR PPARA

Hyperlipidemia NFE2L2 HMGCR PPARG LDLR PPARA

Liver cancer BCL2 NFE2L2 MMP9 CASP3 SOD1 CCND1

Osteosarcoma BCL2 MMP9 CASP3

Oxidative Stress-Related Diseases NFE2L2 PPARG SOD1 GPX1 HMOX1 PPARA

Product description Related Products Prediction Parameters Reference Literature

Product name: Naringin
Synonym name: Naringenin 7-Rhamnoglucoside; Naringoside; Aurantin; Isohesperidin
Catalogue No.: BP0983
Cas No.: 10236-47-2
Formula: C₂₇H₃₂O₁₄
Mol Weight: 580.539
Botanical Source: Aurantii fructus immaturus
Physical Description:
Type of Compound: Flavonoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams
Inquire for bulk scale.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，TCM), Natural Active Pharmaceutical Ingredients worldwide.
The main services:
A. Supply active ingredients and reference standards of TCM, from mgs to kgs scale
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR(contract research), CM(contract manufacture) and PD(process development) services from lab scale, pilot scale to commercial scale(GMP is also available)
E. TCM compounds library for drug screen,more than 3000 compounds available, many of them are rare and unique.