Kaempferol 3-O-gentiobioside

Name: Kaempferol 3-O-gentiobioside
Brand: Phytounique
Rating: 5 (1 reviews)

Catalogue No.： BP3219

CAS NO.: 22149-35-5

Purity: 98%

Brand: Phytounique

Botanical Source:

1. Kaempferol activates LXR-β and suppresses SREBP-1 to enhance symptoms in metabolic syndrome. 2. Kaempferol exerts a potent inhibitory effect on in vitro bone resorption. 3. Kaempferol has anti-inflammatory action, can prevent and treat inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. 4. Kaempferol has therapeutic potential for the prevention and treatment of thrombovascular diseases, can enhance relaxations caused by endothelium-derived and exogenous NO as well as those due to endothelium-dependent hyperpolarization. 5. Kaempferol can inhibit cancer cell invasion through blocking the PKCδ/MAPK/AP-1 cascade and subsequent MMP-9 expression and its activity, may act as a therapeutic potential candidate for cancer metastasis. 6. Kaempferol is an autophagic enhancer, has a more general protection in Parkinson's disease, can mediate antiapoptotic and antioxidant effects is the enhancement of mitochondrial turnover by autophagy. Kaempferol 3-beta-gentiobioside is a kaempferol O-glucoside in which the hydroxy hydrogen at position 3 of kaempferol has been replaced by a gentiobiosyl group. It has a role as a Brassica napus metabolite. It is a trihydroxyflavone, a disaccharide derivative and a kaempferol O-glucoside. It is functionally related to a gentiobiose.

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Catalog No	Package	Original Price	Price	Inventory	Quantity	Operating
BP3219-10mg	10mg	Sign in	Sign in
BP3219-20mg	20mg	Sign in	Sign in

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Related diseases

Type 2 Diabetes Mellitus Osteoporosis Inflammatory disease Cancer Oxidative Stress-Related Diseases

Related targets

Type 2 Diabetes Mellitus PTPN1 NFE2L2 SLC5A2 TNF NOS2 PPARG PTGS2 AKT1 DPP4 IL6 HMOX1 MTOR

Osteoporosis BCL2 NFE2L2 ESR1 TNF NOS2 PPARG MMP9 PTGS2 AKT1 IL6 RUNX2 SP7 TNFRSF11B COL1A1 MTOR KDR

Inflammatory disease PTPN1 NFE2L2 TNF NOS2 PPARG MMP9 PTGS2 AKT1 IL6 HMOX1 MTOR

Cancer PTPN1 BCL2 NFE2L2 TNF NOS2 PPARG MMP9 PTGS2 AKT1 HMOX1 MTOR KDR

Oxidative Stress-Related Diseases NFE2L2 PPARG AKT1 HMOX1

Product description Related Products Prediction Parameters Reference Literature

Product name: Kaempferol 3-O-gentiobioside
Synonym name:
Catalogue No.: BP3219
Cas No.: 22149-35-5
Formula: C₂₇H₃₀O₁₆
Mol Weight: 610.521
Botanical Source:
Physical Description: Yellow powder
Type of Compound: Flavonoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.

Descriptions:
Kaempferol 3-O-gentiobioside (K3G), isolated from C. alata as an abundant flavonoid glycoside, K3G has antiinflammatory activity, shows weak inhibitory effects on Concanavalin A-induced histamine release, 5-lipoxygenase, and COX-1. [1]

References:
[1] Moriyama H, Iizuka T, Nagai M, et al. Yakugaku Zasshi , 2003, 123(7):607-11.
[2] Peng H E, Wang G C, Yao-Lan L I, et al. Central South Pharmacy, 2014(1):66-9.