Isoscopoletin

Name: Isoscopoletin
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP3215

CAS NO.: 776-86-3

Purity: 98%

Brand: Biopurify

Botanical Source: Erigerontis herba

Isoscopoletin is a hydroxycoumarin that is esculetin in which the hydroxy group at position 7 is replaced by a methoxy group. It is the major primary metabolite of scoparone. It has a role as a plant metabolite. It is an aromatic ether and a hydroxycoumarin. It is functionally related to an esculetin. Isoscopoletin possesses inhibitory activity against hepatitis B virus (HBV) replication; it also shows substantial inhibition against multi-drug resistant CEM/ADR5000 cells and human CCRF-CEM leukaemia cells, with the IC50 value is 1.6 and 4.0 microM, respectively.

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Related diseases

Inflammatory disease Analgesia Leukemia Oxidative Stress-Related Diseases Hepatitis B

Related targets

Inflammatory disease STAT3 NFE2L2 TRPV1 MAPK1 TNF PTGS2 NFKB1 AKT1 IL6 HMOX1

Analgesia TRPV1 OPRD1 PTGS2 OPRM1 DRD2 COMT

Leukemia STAT3 NFE2L2 MAPK1 TNF PTGS2 NFKB1 AKT1

Oxidative Stress-Related Diseases NFE2L2 MAPK1 NFKB1 AKT1 HMOX1

Hepatitis B STAT3 NFE2L2 MAPK1 TNF PTGS2 NFKB1 IL6 HBx

Product description Related Products Prediction Parameters Reference Literature

Product name: Isoscopoletin
Synonym name:
Catalogue No.: BP3215
Cas No.: 776-86-3
Formula: C₁₀H₈O₄
Mol Weight: 192.17
Botanical Source:
Physical Description: Powder
Type of Compound: Coumarins

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.