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Irisolidone

BP3669
2345-17-7
98%
Phytounique
Flower of P. thomsonii Benth.
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 uM. Irisolidone shows anti-inflammatory, anti-platelet aggregation, hepatoprotective, and α-amylase inhibitory activities, it may attenuate ethanol-induced gastritis by inhibiting the infiltration of immune cells, particularly neutrophils, through the regulation of CXCL-4 or IL-8 secretion. Irisolidone shows potent inhibitory activity against Helicobacter pylori. Irisolidone also shows antiproliferative activity against amelanotic melanoma cells.
Catalog No Package Original Price Price Inventory Quantity Operating
BP3669-10mg 10mg
BP3669-20mg 20mg
BP3669-100mg 100mg
Chengdu Biopurify Phytochemicals Ltd.
Chengdu Biopurify Phytochemicals Ltd.

Related targets

STAT3 AMPK TNF PPARG PIK3CA PTGS2 NFKB1 IL6 IL1B SOD1
STAT3 TNF PTGS2 NFKB1 IL6 IL1B
BACE1 STAT3 AMPK TNF PPARG PIK3CA PTGS2 NFKB1 SNCA IL6 IL1B SOD1 GRIN1
STAT3 AMPK MMP2 TNF PIK3CA PTGS2 NFKB1 IL6 CDK4 KDR

Product drug property prediction parameters

  • 89.1300

  • 2.3306

  • 2.0617

  • .0121

  • 5.1192

  • 38.0716

  • Low

  • 91.8642

  • 2.3257

  • Yes

  • No

  • Yes

  • No

  • Yes

  • Yes

  • 1.2

  • No

  • No

  • No

  • No