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Glycycoumarin

SBP03544
94805-82-0
98%
Biopurify
Glycyrrhiza Radix Et Rhizoma
Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6. Glycycoumarin has anti-liver cancer, neuroprotective, antioxidant and anti-inflammatory activities. Glycycoumarin has anti-hepatitis C virus (HCV) activity, with the IC(50) value of 8.8, ug/mL. Glycycoumarin has an inhibitory effect on smooth muscle contraction induced by various types of stimulants through the inhibition of PDEs, especially isozyme 3, followed by the accumulation of intracellular cAMP; it also can inhibit hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. Glycycoumarin is a member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 5, a prenyl group at position 6 and a 2,4-dihydroxyphenyl group at position 3. Isolated from Glycyrrhiza uralensis, it exhibits antispasmodic activity. It has a role as an antispasmodic drug and a plant metabolite. It is a member of coumarins, a member of resorcinols and an aromatic ether.
Catalog No Package Original Price Price Inventory Quantity Operating
SBP03544-10mg 10mg
SBP03544-20mg 20mg
SBP03544-100mg 100mg
Chengdu Biopurify Phytochemicals Ltd.
Chengdu Biopurify Phytochemicals Ltd.

Related diseases

Related targets

F2 VKORC1 F7 F9 F10

Product drug property prediction parameters

  • 100.1300

  • 3.7854

  • 3.7423

  • .0491

  • 1.2445

  • 15.6227

  • Low

  • 92.0241

  • 2.7955

  • No

  • No

  • Yes

  • No

  • Yes

  • Yes

  • 0.6

  • Yes

  • Yes

  • Yes

  • No