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Gambogenic acid

BP2014
173932-75-7
98%
Phytounique
Cimicifugae rhizoma
Gambogenic acid is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects, it can cause aberrant autophagy to induce cell death and may suggest the potential application of Gambogenic acid as a tool or viable drug in anticancer therapies.Gambogenic acid could inhibit the proliferation of melanoma B16 cells and induce their apoptosis within certain time and concentration ranges. Its mechanism in inducing the cell apoptosis may be related to PI3K/Akt/mTOR signaling pathways.
Gambogenic acid View larger image
Catalog No Package Original Price Price Inventory Quantity Operating
BP2014-10mg 10mg
BP2014-20mg 20mg
BP2014-100mg 100mg

Contacts：400-829-7929，028-82633860，82633397，82633165

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Chengdu Biopurify Phytochemicals Ltd.
Chengdu Biopurify Phytochemicals Ltd.

Related diseases

Melanoma Breast cancer Colorectal Cancer Non-small cell lung cancer Hepatocellular Carcinoma

Related targets

BCL2 STAT3 PIK3CA MMP9 NFKB1 AKT1 CASP3 BRAF NRAS CDKN2A MITF PTEN CTNNB1 CCND1 MYC CDH1 VEGFA
BCL2 STAT3 ABCG2 PIK3CA MMP9 NFKB1 AKT1 CASP3 PTEN CTNNB1 CCND1 MYC CDH1 VEGFA
BCL2 STAT3 ABCG2 PIK3CA MMP9 NFKB1 AKT1 CASP3 BRAF PTEN CTNNB1 CCND1 MYC CDH1 VEGFA
BCL2 STAT3 ABCG2 PIK3CA MMP9 NFKB1 AKT1 CASP3 BRAF PTEN CTNNB1 CCND1 MYC CDH1 VEGFA
BCL2 STAT3 PIK3CA MMP9 NFKB1 AKT1 CASP3 CDKN2A CTNNB1 CCND1 MYC CDH1 VEGFA
Product description Related Products Prediction Parameters Reference Literature

Synonym name: 
Catalogue No.: BP2014
Cas No.:  173932-75-7 
Formula: C38H46O8
Mol Weight: 630.78
Botanical Source: Gamboge (Garcinia hanburyi)

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams. 

For Reference Standard and R&D, Not for Human Use Directly.

Inquire for bulk scale.

Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃

Product drug property prediction parameters

  • 130.3600

  • 6.7402

  • 3.7270

  • .0420

  • 2.2192

  • 2.6376

  • Low

  • 91.5576

  • 6.4411

  • No

  • Yes

  • Yes

  • No

  • No

  • Yes

  • 0.0

  • No

  • Yes

  • Yes

  • No

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