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Product name: Cimifugin
Synonym name: Cimitin
Catalogue No.: BP0356
Cas No.: 37921-38-3
Formula: C16H18O6
Mol Weight: 306.314
Botanical Source: Bitter principle from the rhizomes of Cimicifuga simplex. Angelica japonica and Ledebouriella seseloides
Physical Description: Powder
Type of Compound: Flavonoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Cimifugin, isolated from Peucedanum schottii, displays low to moderate inhibition towards AChE and BChE (3.12 and 21.63%, respectively) at 200 μg mL-1.[1]
Cimifugin evidently inhibits FITC-induced type 2 allergic contact dermatitis,and its mechanism might related to regulating the balance of Th1 /Th2 by inhibiting type 2 cytokines.[2]
References:
[1] Koziol E, Senol F S, Orhan I E, et al. Natl Prod Communicat, 2016, 6.
[2] Jiang X, Wang H, Gui L, et al. Pharmacol Clin Chinese Mat Med, 2014, 30(2):28-30.
[3] Wang X, Wang Z, Sun H, et al. Arzneimittel-Forschung, 2008, 58(9):445-50.
HPLC of Cimifugin
Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃
89.1300
1.0715
1.0713
.3352
1.1426
6.4954
High
72.9847
3.5333
Yes
No
No
No
Yes
Yes
0.9
Yes
No
Yes
Yes
Shenshuai
Wenjing
Hedandan
