Chebulanin

Catalogue No.： BP2424

CAS NO.: 166833-80-3

Purity: 98%

Brand: 普瑞法

Chebulanin is a topoisomerase I inhibitor, it inhibits the calcineurin pathway in C. neoformans. Chebulanin exhibits potent antifungal activity against various human pathogenic fungi with minimum inhibitory concentrations ranging from 0.25 to over 64 μg/ml. Chebulanin shows strong radical scavenging activity, good potency to chelate Fe2⁺ and good inhibition ability of lipid peroxidation. Chebulanin is a strong therapeutic alternative for the treatment of rheumatism arthritis, it suppresses the expression of inflammatory mediators and prevents cartilage destruction and bone erosion in mice.Chebulanin has anti-cancer acrtivity, it has apparent capacities of inhibiting the survival of MCF-7 human cancer cell line.

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Catalog No	Package	Original Price	Price
BP2424-5mg	5mg	Sign in	Sign in
BP2424-10mg	10mg	Sign in	Sign in
BP2424-20mg	20mg	Sign in	Sign in

Contacts：400-829-7929，028-82633860，82633397，82633165

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Related diseases

Rheumatoid arthritis Breast cancer Fungal infection Oxidative Stress-Related Diseases Cryptococcosis

Related targets

Rheumatoid arthritis BCL2 [object TOP1 TNF NOS2 MMP9 PTGS2 NFKB1 CASP3 IL6 SOD1 PPP3CA

Breast cancer BCL2 TOP1 MMP9 PTGS2 TP53 NFKB1 CASP3

Fungal infection [object TOP1 NFKB1 PPP3CA

Oxidative Stress-Related Diseases [object TP53 NFKB1 SOD1

Cryptococcosis TOP1

Product description Related Products Prediction Parameters Reference Literature

Synonym name: Chebulanin
Catalogue No.: BP2424
Cas No.: 166833-80-3
Formula: C₂₇H₂₄O₁₉
Mol Weight: 652.47
Botanical Source: Tannin derived from divi-divi (fruit of Caesalpinia coriaria) and myrobalans (fruit of Terminalia chebula). Also obtainable from Geranium thunbergii and the seeds of sal (Shorea robusta)

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.