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Bilirubin

BP3455
635-65-4
Bilirubin IXalpha is a member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin. It has a role as an antioxidant, a mouse metabolite and a human metabolite. It is a dicarboxylic acid and a member of biladienes. It contains a 24G7 epitope. Bilirubin is a tetrapyrrole and a breakdown product of heme catabolism, it is a prominent endogenous antioxidant cytoprotectant and a natural inhibitor of vascular smooth muscle cell proliferation, which has neuroprotective and anti- atherosclerosis-related diseases effects. It can act as an effective agent to reduce mortality and counteract hypotension elicited by endotoxin through mechanisms involving a decreased NOS2 induction secondary to inhibition of NAD(P)H oxidase.
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Related diseases

Atherosclerosis Cirrhosis Neurodegenerative disease Antioxidation Jaundice

Related targets

NFE2L2 ACE NFKB1 IL6 NRF2 SOD1 CAT HMOX1 LDLR
NFE2L2 NFKB1 TGFB1 MET CYP2E1
APP NFE2L2 NFKB1 SNCA IL6 NRF2 SOD1 CAT GPX1 HMOX1 SOD2 CYP2E1
NFE2L2 NRF2 SOD1 CAT GPX1 HMOX1 SOD2 CYP2E1
UGT1A1 ABCC2
Product description Related Products Prediction Parameters Reference Literature
Product name: Bilirubin
Synonym name:
Catalogue No.: BP3455
Cas No.: 635-65-4
Formula: C33H36N4O6
Mol Weight: 584.673
Botanical Source:
Physical Description: Powder
Type of Compound: Miscellaneous

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.


Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃

Bilirubin Related Products

Product drug property prediction parameters

  • 164.3800

  • 2.4475

  • -.4693

  • .0649

  • .4831

  • 1.1400

  • Low

  • 89.1851

  • 3.9268

  • No

  • Yes

  • No

  • No

  • No

  • Yes

  • 0.0

  • No

  • Yes

  • Yes

  • Yes

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