Arbutin

Catalogue No.： BP0185

CAS NO.: 497-76-7

Purity: 98%

Brand: Biopurify

Botanical Source: Agrimonia pilosa Ledeb.

Arbutin is a monosaccharide derivative that is hydroquinone attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It has a role as a plant metabolite and an Escherichia coli metabolite. It is a beta-D-glucoside and a monosaccharide derivative. It is functionally related to a hydroquinone. Arbutin is a tyrosinase inhibitor with an IC50 of 1.09 mM, which has gastroprotective, whitening, anti- age, anti-oxidant , anti-inflammatory, a depigmenting effects and UVB/ UVC filter. Arbutin has mutagenicity in mammalian cells after activation by human intestinal bacteria. Arbutin (β - Arbutin) is a widely present natural polyphenol with antioxidant, anti-inflammatory, and anti-tumor properties. Arbutin is a competitive inhibitor of tyrosinase in melanocytes, with a Kiapp value of 1.42 mM for monophenolase and 0.9 mM for diphenolase. Arbutin is also used as a decolorizer.

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Related diseases

Atherosclerosis Liver fibrosis Osteoarthritis Diabetic nephropathy Hyperpigmentation

Related targets

Atherosclerosis TYR CLEC4E AKR1B1 MMP2 SLC5A1 SLC5A2 TNF NOS2 LGALS3 PTGS2 NFKB1 IL1B NRF2

Liver fibrosis PRKCA MMP2 TNF NOS2 PTGS2 NFKB1 IL1B TGFB1 ACTA2 COL1A1 MMP13

Osteoarthritis MMP2 TNF NOS2 PTGS2 NFKB1 IL1B TGFB1 COL1A1 MMP13

Diabetic nephropathy PRKCA AKR1B1 MMP2 SLC5A2 TNF NOS2 PTGS2 NFKB1 IL1B NRF2 TGFB1

Hyperpigmentation TYR PRKCA NRF2 MITF

Product description Related Products Prediction Parameters Reference Literature

Synonym name: Hydroquinone-glucose; Arbutoside; Ericolin
Catalogue No.: BP0185
Cas No.: 497-76-7
Formula: C₁₂H₁₆O₇
Mol Weight: 272.253
Botanical Source: pear leaves (Pyrus communis). Widespread in the Ericaceae, also found in many other plants. First Arctostaphylos uva-ursi in 1852

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.