Apiin

Catalogue No.： BP0182

CAS NO.: 26544-34-3

Purity: 98%

Brand: Phytopurify

Botanical Source:

Apiin is a beta-D-glucoside having a beta-D-apiosyl residue at the 2-position and a 5,4'-dihydroxyflavon-7-yl moiety at the anomeric position. It has a role as an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor and a plant metabolite. It is a beta-D-glucoside, a dihydroxyflavone and a glycosyloxyflavone. It is functionally related to an apigenin. It is a conjugate acid of an apiin(1-). Apiin as a reducing agent, used in biological synthesis of silver and gold nanoparticles. Apiin has anti-inflammatory properties, it has inhibitory activity in-vitro on iNOS expression and nitrite production when added before LPS stimulation in the medium of J774.A1 cells. Apiin is an iNOS inhibitor of flavonoid glycosides. Apiin can inhibit the expression of inducible nitric oxide synthase in activated macrophages. Apiin has anti-inflammatory activity.

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Related diseases

Atherosclerosis Diabetes Mellitus Benign Tumor Inflammatory disease Neurodegenerative disease

Related targets

Atherosclerosis ABCB1 AKR1B1 RELA TNF MAOB NOS2 PPARG PTGS2 IL6 IL1B ICAM1 VCAM1

Diabetes Mellitus ABCB1 AKR1B1 RELA TNF MAOB NOS2 PPARG PTGS2 IL6 IL1B

Benign Tumor ABCB1 AKR1B1 HIF1A TOP2A ABL1

Inflammatory disease RELA TNF NOS2 PPARG PTGS2 IL6 IL1B ICAM1

Neurodegenerative disease RELA TNF MAOB NOS2 ACHE PPARG PTGS2 IL6 IL1B ICAM1

Product description Related Products Prediction Parameters Reference Literature

Product name: Apiin
Synonym name:
Catalogue No.: BP0182
Cas No.: 26544-34-3
Formula: C₂₆H₂₈O₁₄
Mol Weight: 564.496
Botanical Source: Apium graveolens L.
Physical Description:
Type of Compound: Flavonoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams
Inquire for bulk scale.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，TCM), Natural Active Pharmaceutical Ingredients worldwide.
The main services:
A. Supply active ingredients and reference standards of TCM, from mgs to kgs scale
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR(contract research), CM(contract manufacture) and PD(process development) services from lab scale, pilot scale to commercial scale(GMP is also available)
E. TCM compounds library for drug screen,more than 3000 compounds available, many of them are rare and unique.