Amarogentin

Name: Amarogentin
Brand: Phytounique
Rating: 5 (1 reviews)

Catalogue No.： BP1603

CAS NO.: 21018-84-8

Purity: 98%

Brand: Phytounique

Botanical Source:

Amarogentin incorporated in liposomes or niosomes may have clinical application in the treatment of leishmaniasis. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis. Amarogentin may offer therapeutic potential for preventing or treating thromboembolic disorders, it prevents platelet activation through the inhibition of PLC γ2-PKC cascade and MAPK pathway. Amarogentin is a secoiridoid glycoside that consists of (4aS,5R,6R)-5-ethenyl-6-hydroxy-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one having a 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranosyl group attached at position 6 via a glycosidic linkage. It has a role as a metabolite and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It is a secoiridoid glycoside and a monosaccharide derivative.

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Catalog No	Package	Original Price	Price	Inventory	Quantity	Operating
BP1603-20mg	20mg	Sign in	Sign in
BP1603-100mg	100mg	Sign in	Sign in

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Related diseases

Type 2 Diabetes Mellitus Non-alcoholic fatty liver disease Liver fibrosis Anti-inflammatory Colorectal Cancer

Related targets

Type 2 Diabetes Mellitus PTPN1 AMPK NFE2L2 TNF PPARG PIK3CA SREBF1 PTGS2 NFKB1 AKT1 IL6 IL1B TGFB1 SLC2A4 MTOR PPARA

Non-alcoholic fatty liver disease PTPN1 AMPK NFE2L2 TNF PPARG PIK3CA SREBF1 PTGS2 NFKB1 AKT1 CASP3 IL6 IL1B TGFB1 SLC2A4 CPT1A ACTA2 CYP2E1 MTOR PPARA

Liver fibrosis AMPK MMP2 NFE2L2 TNF PPARG PIK3CA PTGS2 NFKB1 AKT1 CASP3 IL6 IL1B TGFB1 ACTA2 CYP2E1 BAX CDK1

Anti-inflammatory TNF PTGS2 NFKB1 IL6 IL1B

Colorectal Cancer AMPK MMP2 NFE2L2 TNF PPARG PIK3CA PTGS2 NFKB1 AKT1 CASP3 IL6 TGFB1 CTNNB1 BAX MTOR PPARA CDK1

Product description Related Products Prediction Parameters Reference Literature

Product name: Amarogentin
Synonym name:
Catalogue No.: BP1603
Cas No.: 21018-84-8
Formula: C₂₉H₃₀O₁₃
Mol Weight: 586.546
Botanical Source: Gentiana sp. and Swertia japonica
Physical Description: Powder
Type of Compound: Iridoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.