7-Ethyl-10-Hydroxycamptothecin

Catalogue No.： BP0099

CAS NO.: 86639-52-3

Purity: 98%

Brand: Biopurify

Botanical Source: Salviae Miltiorrhizae Radix et Rhizoma

7-Ethyl-10-Hydroxycamptothecin is a member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. It has a role as an antineoplastic agent, a drug metabolite, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an apoptosis inducer. 7-Ethyl-10-hydroxycamptothecin shows cytotoxicity against breast cancer, it efficiently target-bind to the colon and lungs of mice.

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Catalog No	Package	Original Price	Price
BP0099-20mg	20mg	Sign in	Sign in
BP0099-100mg	100mg	Sign in	Sign in
BP0099-1000mg	1000mg	Sign in	Sign in

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Related diseases

Rheumatoid arthritis Colorectal Cancer Pancreatic cancer Glioblastoma Small Cell Lung Cancer

Related targets

Rheumatoid arthritis BCL2 ABCG2 TOP1 HIF1A HDAC6 CASP9 HBB CASP3

Colorectal Cancer BCL2 ABCG2 TOP1 HIF1A CASP9 TP53 ABCC1 CASP3 PARP1 ATM

Pancreatic cancer BCL2 TOP1 HIF1A CASP9 TP53 CASP3 PARP1 ATM

Glioblastoma BCL2 ABCG2 TOP1 HIF1A TP53 ABCC1 CASP3 MGMT

Small Cell Lung Cancer BCL2 ABCG2 TOP1 CASP9 TP53 CASP3 PARP1 ATM

Product description Related Products Prediction Parameters Reference Literature

Synonym name: 10-Hydroxy-7-ethylcamptothecin; 7-Ethyl-10-hydroxy-20(S)-camptothecin
Catalogue No.: BP0099
Cas No.: 86639-52-3
Formula: C₂₂H₂₀N₂O₅
Mol Weight: 392.411
Botanical Source:

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.