5-Hydroxy-4-methoxycanthin-6-one

Catalogue No.： SBP00616

CAS NO.: 18110-86-6

Purity: 98%

Brand: 普瑞法

4-Methoxy-5- hydroxycanthin-6-one has anti-inflammatory effect, it can significantly inhibit the production of NO and the release of TNF-α induced by LPS in macrophage RAW 264.7, it has protective effect on dextran sulfate sodium -induced rat colitis. After oral administration, 4-methoxy-5- hydroxycanthin-6-one (3, 9, and 27 mg/kg) can reduce the development of carrageenan-induced paw edema and complete Freund's adjuvant (CFA)-induced chronic arthritis in rats. 5-Hydroxy-4-methoxycanthin-6-one exhibits significant cytotoxic activity against CNE2 cell line.

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SBP00616-5mg	5mg	Sign in	Sign in
SBP00616-10mg	10mg	Sign in	Sign in
SBP00616-20mg	20mg	Sign in	Sign in

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Related diseases

Inflammatory disease Antimalarial Cancer Neurodegenerative disease Viral Infections

Related targets

Inflammatory disease STAT3 ALOX5 NFE2L2 PTGS1 TNF NOS2 PPARG MMP9 PTGS2 NFKB1 AKT1 IL6 IL1B HMGB1

Antimalarial PFCRT PFMDR1 PFDHFR PFATP6 PFCYTb

Cancer BCL2 STAT3 ALOX5 NFE2L2 TOP1 TNF NOS2 PPARG MMP9 EGFR PTGS2 TP53 NFKB1 AKT1 CDK2 CASP3 HMGB1

Neurodegenerative disease BACE1 BCL2 STAT3 MAPT ALOX5 NFE2L2 BCHE TNF MAOB NOS2 ACHE PPARG EGFR PTGS2 NFKB1 AKT1 CASP3 SNCA IL6 IL1B BDNF GRIN1

Viral Infections NFKB1 AKT1 IL6 NA UL30 NS5B POL NS5

Product description Related Products Prediction Parameters Reference Literature

Product name: 5-Hydroxy-4-methoxycanthin-6-one
Synonym name:
Catalogue No.: SBP00616
Cas No.: 18110-86-6
Formula: C₁₅H₁₀N₂O₃
Mol Weight: 266.256
Botanical Source:

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.

Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃