| 产品名称 | VIMENTIN Recombinant antibody, Fibroblast marker |
|---|---|
| 产品编号 | HB50317 |
| Uniprot ID | P08670 |
| Host Species | Rabbit |
| Reactivity | human, mouse, rat |
| Tested Applications | IHC |
| Application | IHC :1:100 -1:200 |
| Background | Vimentin is a structural protein that in humans is encoded by the VIM gene. Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all animal cells as well as bacteria. Intermediate filaments, along with tubulin-based microtubules and actin-based microfilaments, comprises the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastatic progression. |
| Alternative Names | VIM |
| Immunogen | Synthetic Peptide |
| Subcellular Localization | Cytoplasm |
| Conjugate | Unconjugated |
| Purification | Protein A affinity purified |
| Formulation | Liquid |
| Storage | Store at -20°C |
| Figure ID 1 | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
| Figure ID 2 | HB50317 |
| 保质期 | 12 months |
