| 产品名称 | YY1 Polyclonal antibody |
|---|---|
| 产品编号 | HB30030 |
| Uniprot ID | P25490 |
| Host Species | Rabbit |
| Reactivity | human, mouse, rat, pig, bovine |
| Tested Applications | WB, IHC, IF/ICC, IP, ELISA |
| Application | WB : 1:500-1:2000 IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate IHC : 1:50-1:500 IF/ICC : 1:50-1:500 |
| Background | YY1, also named as DELTA, INO80S and NF-E1, contains four C2H2-type zinc fingers and belongs to the YY transcription factor family. YY1 is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the YY1. The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However, YY1 migrates on SDS gels as a 65-68 kDa protein, probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis, differentiation, replication and proliferation. This is a rabbit polyclonal antibody raised against full length YY1 of human origin. |
| Alternative Names | DELTA, Delta transcription factor, INO 80S, INO80S, NF-E1 |
| Immunogen | Recombinant human YY1 protein |
| Calculated MW | 414 aa, 45 kDa |
| Observed mw | 65-70 kDa |
| Subcellular Localization | Nuclear |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Formulation | Liquid |
| Storage | Store at -20°C |
| Figure ID 2 | HB30030 |
| 保质期 | 12 months |
