| 中文名称 |
Rabbit Polyclonal anti-Phospho-PLB(T17) Antibody |
| 英文名称 |
Rabbit Polyclonal anti-Phospho-PLB(T17) Antibody |
| 检测范围 |
6.1 kDa |
| 灵敏度 |
Human |
| 免疫原 |
The PLB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T17 of human PLB. |
| 应用范围 |
Dot |
| 克隆性 |
Polyclonal |
| 物种 |
Rabbit |
| 储存条件 |
Store at -20°C as received. |
Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.